Choline is a fat-soluble compound found in the membrane phospholipids of all tissues. Choline is involved in the body in for example the metabolism of fat and cholesterol, and acts in the structures of plasma membranes as well as in inter-cellular communication. All natural fats contain some choline in the form of phosphatidylcholine.
The main sources of choline are meat, dairy, eggs and grains. The 2024 National Dietary Guidelines set a recommended intake of 400 mg of choline per day for adults.