Aims:
The purpose of the project is to develop LC-MS/MS methods for the determination of the enantiomers of ketoprofen and budesonide in animal plasma. The projects are part of cooperation projects launched for the examination of the clinical phase, pharmacokinetics and toxicology of ketoprofen and the use of the budesonide inhaler in the treatment of canine asthma.
Keywords:
ketoprofen, budesonide, plasma, LC-MS/MS
Responsible project leader:
Kimmo Peltonen, Professor, Evira, Chemistry and Toxicology Research Unit
Persons at Evira responsible for the project:
Berg, Seija, Senior Researcher, (budesonide), Chemistry and Toxicology Research Unit;
Niemi, Anneli, Researcher, (ketoprofen), Chemistry and Toxicology Research Unit
Contact persons at Evira:
Peltonen, Kimmo, Professor, Chemistry and Toxicology Research Unit;
Berg, Seija, Senior Researcher, (budesonide), Chemistry and Toxicology Research Unit;
Niemi, Anneli, Researcher, (ketoprofen), Chemistry and Toxicology Research Unit
In cooperation with:
Vainio, Outi, Professor, (budesonide, ketoprofen), University of Helsinki, Faculty of Veterinary Medicine;
Melamies, Marika, Lic.V.M., (budesonide), University of Helsinki, Faculty of Veterinary Medicine;
Mustonen, Katja, Lic.V.M., (ketoprofen), University of Helsinki, Faculty of Veterinary Medicine
Project status:
Previous
Year of commencement:
2007
Year of completion:
2011
Publications:
E. Lindfors, A. Niemi
Determination of lincosamides in milk by LC-MS/MS.
EuroResidue VI Conference on Residues of Veterinary Drugs in Food, (19. – 21.5.2008 : Egmond am See, The Netherlands).
Abstract in Proseedings. Poster.